FROM STRATEGIC ASSOCIATION TO THE CRISIS: SPANISH-BRAZILIAN RELATIONS IN A CONTEXT OF STRUCTURAL CHANGE


Mitochondrial Dysfunction and Oxidative Stress in Asthma: Implications for Mitochondria-Targeted Antioxidant Therapeutics

Asthma is a complex, inflammatory disorder characterized by airflow obstruction of variable degrees, bronchial hyper-responsiveness, and airway inflammation.Asthma is caused by environmental factors and a combination of genetic and environmental stimuli.Genetic studies have revealed that multiple loci are involved in the etiology of asthma.Recent B

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Variants Disrupting CD40L Transmembrane Domain and Atypical X-Linked Hyper-IgM Syndrome: A Case Report With Leishmaniasis and Review of the Literature

X-linked hyper-IgM (XHIGM) syndrome is caused by Aftershave mutations of the CD40LG gene, encoding the CD40L protein.The clinical presentation is characterized by early-onset infections, with profound hypogammaglobulinemia and often elevated IgM, susceptibility to opportunistic infections, such as Pneumocystis jirovecii pneumonia, biliary tract dis

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